APPROACH AND METHODOLOGY
This commitment seeks to accomplish the following:
1. Establish Personalized Medicine at the King Hussein Cancer Center in Amman, Jordan.
2. Treat cancer using the most advanced medical treatment available.
3. Expand research capacity for the region as well as collaborate with international research institutes.
This will require:
- Establishing physical infrastructure through the purchase of machinery and construction of specifically designed spaces at KHCC
- Addressing human resource needs through the training of doctors
- Advancing innovation through international collaboration and research
IMPLEMENTATION, TIMELINE, AND DELIVERABLES
The establishment of Personalized Medicine at KHCC will be conducted in two phases. The first phase will begin in the first quarter of 2011. It will take approximately six months for both the physical infrastructure and human resource elements to be in place, and then treatment will begin. The second phase will begin during the first quarter of 2013.
- Establishment of an Institute/Office of Personalized Medicine at KHCC, including hiring director and staff.
- Purchase and installation of Tissue Bank and Bio Repository
- Purchase and installation of full Genetic and Molecular Diagnostic Laboratory
- Train doctors, technicians, and staff
- Research: focus research on identifying certain aspects of cancer that are distinctive to the Middle East gene pool, specifically with regards to inherited cancers
- Facilitate research projects by adding tissues from the Middle Eastern region to larger research projects throughout the world.
In order to make this treatment approach a reality, proper investment in technological infrastructure and training must occur, beginning with the Tissue Bank and Bio Repository as well as the Genetic and Molecular Diagnostic Laboratories. The Diagnostic Laboratories will help doctors properly analyze patients' tissue, enabling them to more adequately establish an appropriate treatment plan. The remaining tissues and bio samples will be stored in the Tissue Bank and Bio Repository for research purposes. In addition, patient specifications will be logged into a corresponding database enabling researchers to perform in-depth analysis of tissue samples and track long-term cancer trends.
These programs are the first steps in advancing Personalized Medicine and promoting evidence-based management of cancer treatment. Through Personalized Medicine, KHCC's leading doctors will be able to make significant contributions to cancer treatment and research on a local, regional, and international scale.
When it comes to cancer, 'The chance for a cure, the chance to live, should not be an accident of geography or demographics.' The King Hussein Cancer Foundation and Center in Amman, Jordan believe that all people deserve the opportunity to receive the highest quality of treatment no matter where they live. This is why they treat patients with the latest technology and are leading the region in establishing the most innovative approaches to cancer care.
Given that by the year 2020, there will be an estimated 674,937 new cases of cancer in the Middle East with cancer rates rising faster than population growth; cancer has become one of the most critical health issues of the 21st century. Despite advancements in science, current treatments often involve heavy doses of chemotherapy, radiation therapy, and surgery which often produce high levels of toxicity causing both short and long-term complications. To combat these side effects, improve patient outcomes, and more accurately treat each individual cancer patient, a new approach called 'Personalized Medicine' is being developed. This approach uses molecular testing methods to determine the genetic/protein make-up of a tumor and how it relates to the specific individual, thus allowing doctors to determine with greater precision specific treatment plans and avoid unnecessary treatments and surgeries.