New research from Columbia University is challenging long-held assumptions about alcohol, including what “moderate” really means and whether there’s a safe number of drinks for men and women. What does the evidence actually tell us about alcohol? Why are drinking patterns changing? And as more people reach for THC instead of alcohol, what do we know about the tradeoffs? To help us separate fact from fiction, Chelsea speaks with the study’s author, Dr. Katherine Keyes, a professor at Columbia University whose research focuses on psychiatric and substance-use epidemiology.