An individual holds a bag of medical supplies

Overdose Response Network

Fighting the overdose epidemic

An individual holds a bag of medical supplies


The U.S. overdose crisis is among the most pressing and indiscriminate health challenges of our time. More than one million people have died from a drug overdose since 1999.

Overdose deaths are preventable, and solutions to the crisis lie within our own communities. The Clinton Foundation, with over 15 years of experience tackling complex health challenges, is uniquely positioned to help communities across the U.S. reduce stigma and save lives.

Join the Network

Interested in joining the fight to end the overdose crisis in the United States? Send us a note to learn how you might partner and participate in the Overdose Response Network.

In Photos: Overdose Response Network in Action

President Clinton speaks with a doctor inside a medical center
President Clinton speaks onstage with a panel
President Clinton speaks with an individual
An individual presents in front of a screen that says "What is naloxone (Narcan)?"
Individuals speak onstage at an event
President Clinton speaks with an individual holding a backpack that says "emergency medical response"
Two individuals speak with one another
President Clinton and several individuals speak with one another
Individuals stand behind a folding table at a Drug Take Back Day event
Close-up of hands holding a pouch with naloxone nasal spray
President Clinton speaks with individuals outside a mobile care unit
Individuals gather and dispose of medications at a Drug Takeback Day event
Elijah Cummings speaks onstage
A staff member presents to a group


Fighting the overdose crisis requires a comprehensive, sustainable approach and we believe that everyone can play an important part in charting a better path forward for victims, families, and communities across the country. We bring together diverse groups of stakeholders to implement solutions aimed at reversing the crisis and increasing access to naloxone and other lifesaving resources by expanding our work with schools, faith leaders, and communities.

  • 1

    Expanding Naloxone Access

    Naloxone is the medication that reverses the physical effects of an opioid overdose. We’ve negotiated innovative agreements with manufacturers of naloxone to lower the cost and have formed partnerships to increase affordability and expand distribution of this critical, lifesaving treatment. Learn more >

  • 2

    Engaging Community Leaders

    Faith leaders are a trusted source of support and information. They influence attitudes and practices in communities across the U.S., and as such, are a vital part of the solution to confronting the overdose crisis. We’re working to build networks of faith leaders representing different faith traditions, and equip them with the knowledge, skills, and resources needed to organize community members, reduce the stigma of addiction, and fight substance use disorders in their communities. Learn more >

  • 3

    Translating Research into Practice

    We bring together experts from across sectors to research, compile, and disseminate the best available science on substance use disorders. Learn more >


At the Clinton Foundation, we believe data should be used to guide how programs are designed and implemented. We leverage both quantitative and qualitative information in order to promote evidence-based decision-making and help the Foundation and our community of partners achieve greater results in people’s lives across the country and around the world.

  • 861K


    distributed to recovery residences, high schools, universities, and community organizations through the Overdose Response Network in partnership with Direct Relief, Emergent BioSolutions, and the Voices Project.

  • 220


    engaged across 8 US cities to equip them with the skills and resources needed to organize community members, reduce the stigma of addiction, and confront substance use disorders in their communities.